| 1880 | Novelist Percy Greg writes Across the Zodiac: an early science fiction story about a space traveler who goes to Mars with plants. This is one of the earliest mentions of plants in space. |
| 1895 | Russian scientist Konstantin Tsiolkovsky speculates about orbital greenhouses in space in “Grezy o Zemle i Nebe” (Dreams of Earth and Sky). |
| 1945 | Soviet astronomer Gavriil Adrianovich Tikhov coined the term astrobotany (1945) and founded the Department of Astrobotany at Alma-Ata Observatory (1947). |
| 1946 | Harvard biologists and U.S Naval scientists team up to launch the first seeds on repurposed V-2 rockets at White Sands, New Mexico. |
| 1947-48 | Researchers at the University of Chicago-Illinois sent lily, mustard, and radish seeds towards the edges of Space with flights to between 65000-100,000 feet on a series of unmanned balloon experiments. |
| 1954 | Jack Myers tests algae for bioregenerative life support systems for the USAF and NASA. This is the beginning of a space agency’s first serious interest in utilizing plants in life support. |
| 1971 | 500 tree seeds were flown around the Moon on Apollo 14. These will be planted on Earth upon their return and are referred to as Moon Trees. |
| 1973 | Students in Nebraska and California collaborate with NASA to observe rice growth in space as part of Skylab Student Experiment ED-61/62 Plant Growth/Plant Phototropism. |
| 1982 | Soviet cosmonauts grew Arabidopsis onboard Soviet Salyut 7. These are the first plants to produce seeds and flowers in space. The Plant Growth Unit (PGU) was launched, beginning a 15-year streak of astrobotany experiments. This was the first American platform to run regular flight experiments for biological life support systems. |
| 1989 | ESA’s Micro-Ecological Life Support System Alternative (MELiSSA) established. |
| 1995 | NASA begins using BRIC (Biological Research in Canisters). Arabidopsis will be flown using this hardware. |
| 1997 | The Plant Growth Unit (PGU) was retired. Its successor, the Plant Growth Facility (PGF) was first flown during this year. |
| 2002 | Establishment of the Arthur Clarke Mars Greenhouse (ACMG) in the Canadian High Arctic |
| 2014 | Data retrieved from BRIC19 aboard the ISS yield the first complete transcriptome RNA sequencing of Arabidopsis thaliana, allowing for the monitoring of every single gene in Arabidopsis. |
| 2016 | Zinnia blooms aboard the International Space Station under the care of U.S. astronaut Scott Kelly. |
| 2019 | Cotton sprouts and quickly dies aboard Chang’e, the first spacecraft to land on the dark side of the moon. This is the first known astrobotany experiment performed on the lunar surface. |
| 2021 | First legume nodulation experiment in space; first peppers grown in space |
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Let's grow plants in space.